“On” vs “Off” times.

"On" times, also known as "good on" times, are periods of time when Parkinson's medications are effective and symptoms are minimal or non-existent. "Off" times are when symptoms return between medication doses, and can include muscle stiffness, slowed movement, shuffling, freezing, or “feeling stuck”. "Off" times can occur gradually before the next dose of medication is scheduled, or suddenly and randomly.